I use dual monitors, 1080p / 60fps landscape on left, 1080p portrait on the other. Using splits and wallpapers on both. However, the monitor will not fully switch to portarait without logging out. The image on the monitor flips correctly, so it looks right... but the mouse doesn't see that and continue to enter from the short-side (top) rather than see it as being in portrait mode. This also breaks the mouse function on that monitor as it doesn't actually know where anything is located. I've tried this without splits, and just dual monitors and the flipped one always requires logging-out or "switching" users (faster).

I'm on

Windows 10 (22H2) [19045.5073]
Windows Version Parts: 19045.5073
Windows Build Label: 19041.vb_release.191206-1406