* For example Titlebar buttons; I can no longer choose from a list of icons but just browse image files. Why? And why are they not still in the functions tab? That's where they make sense because that's what they trigger.
* Windows 10 - there are two checkboxes and one textbox. Does it really need a separate tab?
* Our apps - Why a tab? Make a button in the "About" tab, it makes sense there.
* Apply button is gone - Why? "Close" could imply that the user might need to find a "Save" or "Apply" button somewhere else and might lose changed options if failing to do so.
* Desktop Icon Profiles - An empty list and a "Save" button. Finally a "Save" button! Wait... What does it save? Oh, it DOESN'T save, it ADDS something. What does it add? I have no idea, but I could give it a name. I am severly confused.

I am halfway through the tabs and I don't feel like I need to find further points. Whomever suggested the re-arrangement should be voted down and reconsider IMO. Either that, or give us an option to use the "old" layout. This is infinitely worse.
I don't know if I can downgrade without losing my settings either - so I don't know if I can uninstall the beta and install the last stable version without having to dedicate an hour setting everything up.