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If you usually have a phone or a tablet handy, you could use the
DisplayFusion Remote app to run the "Monitor Configuration > Load Monitor Profile: Profile Name" function. I've just tested it here and it works fine at the lock screen (assuming it's locked, and not fully logged out).
If you go that route, you'll want to enable the "Monitor Configuration > Don't Show Confirmation Prompt" option in the Settings > Advanced Settings window, otherwise it will revert back to the old profile if you don't login and click Keep Changes fast enough
Hope that helps!