Please can someone tell me what I am missing?

I have never been able to use the hotkey to load. Many different combinations have been tried.

Is there some switch that needs to be enabled?

Thanks.

They were ticked on both PCs. However, I tried a different combination of keys and it now works.
I am happy to have made a fool of myself just to have it work for me!
I have lost count of the number of years I have been trying.
CTRL WIN ALT 1 works for me now. I must just have been unlucky with my previous choices.
Thank you.